By C. Trent Rosecrans
With runners on first and second and no outs, Chicago's Alexi Ramirez tried to lay down a bunt, but hit more of a short liner. Santana, charging in from first, dove to make the catch and then doubled up the runner by throwing to a covering Orlando Cabrera to force A.J. Pierzynski at first. Cabrera then went to shortstop Asdrubal Cabrera to triple up Carlos Quentin.
The White Sox hadn't hit into a triple play since 1978, when the Blue Jays tripled up the White Sox.
Video of the play can be seen here.
Santana was 2 for 4 at the plate, as well, in a 7-1 Indians victory.For more baseball news, rumors and analysis, follow @cbssportsmlb on Twitter or subscribe to the RSS feed.